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Researching the Key to Life
3/29/2007
 Several UST alumni play integral roles in the rich history of high throughput genomic sequencing at the Human Genome Sequencing Center, established by Richard Gibbs, Ph.D. in 1996. The HGSC at Baylor College of Medicine, in the Department of Molecular and Human Genetics, is one of three National Institutes of Health-funded genome centers that were involved in the completion of the first human genome sequence.
The Center was responsible for elucidating and assembling 10 percent of the human genome in addition to completing the genomes of other model organisms including rat, two species of drosophila, honey bee, sea urchin, bovine and macaque.
Christian Buhay, B.S. biology ’99, is a senior scientific programmer in the Assembly Finishing Core. He has assembled all of the genomes that have been completed to a finishing level and has created software tools to increase efficiency and productivity. Maggie Morgan, B.A. biology ’99, is a project manager for the Medical Re-sequencing Initiative. The goal of this initiative is to determine the genomic changes involved in disease through PCR-based sequencing. Joe Chacko, B.A. biology ’98, is a senior lab supervisor overseeing one of two production teams responsible for generating 4.5 million sequencing reads per month.
Angie Garcia, B.A. math and B.S. biology ’00, is a senior scientific programmer. She has spent her time at the Center developing a production and information pipeline for the Mammalian Gene Collection. The program is a multi-institutional effort to identify and sequence human, mouse and rat genes.
“These alumni have been part of Baylor's genomics facility since graduation. Our whole liberal arts community is proud of their accomplishments,” said Dr. Don Frohlich, professor and chair of biology.
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